Anabrez lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body. Anabrez is used to treat breast cancer in postmenopausal women. It is often given to women whose cancer has progressed even after taking Tamoxifen.
Take Anabrez by mouth with or without food, usually once a day, or as directed by your doctor. Use this medication regularly in order to get the most benefit from it. Remember to use it at the same time each day. Do not increase your dose or take Anabrez more often without your doctor’s approval. Your condition will not improve any faster and the risk of serious side effects may be increased. Since Anabrez can be absorbed through the skin, women who are pregnant or who may become pregnant should not handle or break the tablets of Anabrez.
Hormones are chemical substances that are produced by glands in the body, which enter the bloodstream and cause effects in other tissues. For example, the hormone testosterone made in the testicles and is responsible for male characteristics such as deepening voice and increased body hair. The use of hormone therapy to treat cancer is based on the observation that receptors for specific hormones that are needed for cell growth are on the surface of some tumor cells. Hormone therapies work by stopping the production of a certain hormone, blocking hormone receptors, or substituting chemically similar agents for the active hormone, which cannot be used by the tumor cell. The different types of hormone therapies are categorized by their function and/or the type of hormone that is effected.
Anastrozole is an aromatase inhibitor. This means it blocks the enzyme aromatase (found in the body’s muscle, skin, breast and fat), which is used to convert androgens (hormones produced by the adrenal glands) into estrogen. In the absence of estrogen, tumors dependent on this hormone for growth will shrink.
Side effects: hot flashes; joint pain or stiffness; weakness; sore throat; depression, mood changes; nausea; or back pain, bone pain.